Mechanism of Disease (2:09 min)
An overview of the role of KRAS G12C in cancer
The Evolving Landscape of Biomarkers in NSCLC (00:59 seconds)
A short educational video on the evolving landscape of biomarker testing in NSCLC providing an overview of actionable biomarkers
KRAS G12C is a Molecular Biomarker in NSCLC (00:48 seconds)
A short educational video providing an overview of the KRAS gene and the KRAS G12C mutation
Clinical Guidelines Recommend Biomarker Testing in All Appropriate Patients With NSCLC (1:15 min)
A short educational video on comprehensive biomarker testing in NSCLC and clinical guideline recommendations
Biomarkers Can Be Detected Using Either Tissue or Liquid Biopsy Samples (1:13 min)
A short educational video describing how biomarkers can be detected using either liquid or tissue biopsies and how to interpret results
Comprehensive Biomarker Testing is a Key Component to the Care of Patients With Advanced NSCLC (1:16 min)
A short educational video describing the value of comprehensive biomarker testing and the importance of knowing your patient's biomarker status in NSCLC
Leading the Way in NSCLC Biomarker Testing: An Educational Resource for Advanced Practice Providers (9:35 min)
An educational and interactive summary for advanced practice providers (APP) that offers insight into testing considerations, how to set expectations with patients, and receiving and reviewing test results in NSCLC
Featuring Andrew S. Guinigundo, an APP and Director of Precision Oncology at Cincinnati Cancer Advisors
Exploring Biomarker Testing in NSCLC: Actionable Biomarkers and Current Testing Guidelines (3:16 min)
An educational medical short for healthcare professionals about actionable biomarkers, biomarker testing, and current biomarker testing guidelines in advanced NSCLC
Featuring Dr. Ticiana Leal from the Winship Cancer Institute at Emory University School of Medicine
Examining Biomarker Testing Gaps in NSCLC (3:57 min)
An educational medical short for healthcare professionals about guideline recommendations, the benefits of broad biomarker testing, and current biomarker testing patterns and gaps in advanced NSCLC
Featuring Dr. Ticiana Leal from the Winship Cancer Institute at Emory University School of Medicine
Overcoming Biomarker Testing Barriers in NSCLC (5:04 min)
An educational medical short for healthcare professionals about biomarker testing methods, testing barriers, and considerations to overcome testing barriers in advanced NSCLC
Featuring Dr. Ticiana Leal from the Winship Cancer Institute at Emory University School of Medicine
Overcoming Testing Challenges in the Rapidly Evolving Landscape of NSCLC (10:20 min)
An overview of biomarker testing in NSCLC, including the most common barriers to testing and how to overcome them
Key Considerations in Biomarker Testing Journey in NSCLC (10:29 min)
A podcast featuring Dr. Pranil K. Chandra, who discusses the importance of testing, practice considerations for tissue preservation, and scenarios where liquid biopsy may be preferred
Considerations for Biomarker Testing in NSCLC (11:00 min)
A podcast featuring Dr. David R. Braxton, who discusses the importance of biomarker testing in clinical practice, improving turnaround time, and strategies for documentation
Have You Tested Your NSCLC Patients for All Actionable Biomarkers? (00:29 seconds)
A short animated video reminding healthcare professionals to test their eligible NSCLC patients for all actionable biomarkers
A resource that contains an overview of the biomarker testing landscape in NSCLC, including prevalence, guideline recommendations, and considerations for testing
A presentation providing disease state education on NSCLC biomarkers, identification, and testing
A brochure that outlines procedural elements of the testing process, such as verifying coverage, verifying benefits, and billing, as well as a sample billing and coding form
A 2-page document that summarizes how to test, record, and report on KRAS G12C as part of a biopsy, as well as a list of reference labs in the United States that test for KRAS G12C
A resource that outlines the coverage for
next-generation sequence testing for many commercial
and Medicare insurance plans. The resource also includes a chart of steps for support coverage and prior
authorization information
A resource developed by LUNGevity that can be used when discussing comprehensive biomarker testing with patients, featuring common questions patients may have and how to answer them
A resource developed by LUNGevity about comprehensive biomarker testing for your patients with lung
cancer. It also includes helpful tips on when to use biomarker testing and some current barriers that
you may face. Please see an additional reference to support the information in this factsheet: Billingy
NE,
et al. Cancers (Basel). 2021;13:4282.
A longer-form guide providing a detailed overview of NSCLC biomarker testing. The overview incorporates data and guideline recommendations. These are enhanced further by perspectives and considerations on testing topics from expert faculty Maria E. Arcila, MD, Mark A. Socinski, MD, and Lauren Welch, MSN, NP-C, AOCNP
A single-page resource that lists and explains practice gaps in offering targeted therapy to patients with NSCLC. Please see an additional reference to support the information in this resource: Sadik H, et al. JCO Precision Oncology. 2022;6:e2200246.
A wallet card for patients to complete with their care team to help keep track of their individual biomarker status and facilitate conversations
A patient-focused disease state education resource that helps inform patients about biomarker testing, the KRAS G12C mutation, and other helpful guidance about these topics
A brief but detailed overview featuring questions and answers for patients about the purpose of biomarker testing, what testing for KRAS G12C is meant to accomplish, and how to get tested
A 2-page outline that offers step-by-step guidance for a patient's journey through metastatic NSCLC, including testing, biomarker analysis, and personalized therapy. The second page includes a list of questions for a patient to ask their healthcare providers during each step of the journey. This educational resource was developed in partnership with The Academy of Oncology Nurse and Patient Navigators®
An informative list of frequently asked questions that patients may have about biomarker testing developed by LUNGevity. The flashcard may help provide patients with a clearer understanding of what occurs with biomarker testing and may help better inform their treatment decisions
LUNGevity has developed a patient-directed overview about biomarker testing, what is involved, and what to expect with the testing process
A short discussion guide created by LUNGevity to help patients navigate conversations with their healthcare providers. The questions offer a linear path to help patients understand what tests they may need and what the results of those tests mean for them
A LUNGevity-created summary of patients' rights and considerations when undergoing comprehensive biomarker testing. This Bill of Rights helps set expectations for patients who may not be familiar with the process of biomarker testing
A resource offering support and guidance around a patient's lung cancer diagnosis. The resource looks at potential obstacles stemming from others' reactions to the news, how to cope with or overcome those obstacles, and other organizations or outlets that offer support for patients
A conversation guide for patients to use when talking about their lung cancer diagnosis with their doctor. The guide provides a detailed list of potential care team members and their roles, topics to discuss with members of their care team, helpful questions to ask, and other organizational tools and skills for the patient to help themselves and to help others help them
*These third-party resources are for your information only. Amgen does not endorse and is not responsible for the content included in these resources.
KRAS, Kirsten rat sarcoma; NGS, next-generation sequencing; NSCLC, non-small cell lung cancer.
