KRAS G12C mutation patient and physcian resources

Videos and podcasts

Mechanism of Disease (2:09 min)

An overview of the role of KRAS G12C in cancer

The Evolving Landscape of Biomarkers in NSCLC (00:59 seconds)

A short educational video on the evolving landscape of biomarker testing in NSCLC providing an overview of actionable biomarkers

KRAS G12C is a Molecular Biomarker in NSCLC (00:48 seconds)

A short educational video providing an overview of the KRAS gene and the KRAS G12C mutation

Clinical Guidelines Recommend Biomarker Testing in All Appropriate Patients With NSCLC (1:15 min)

A short educational video on comprehensive biomarker testing in NSCLC and clinical guideline recommendations

Biomarkers Can Be Detected Using Either Tissue or Liquid Biopsy Samples (1:13 min)

A short educational video describing how biomarkers can be detected using either liquid or tissue biopsies and how to interpret results

Comprehensive Biomarker Testing is a Key Component to the Care of Patients With Advanced NSCLC (1:16 min)

A short educational video describing the value of comprehensive biomarker testing and the importance of knowing your patient's biomarker status in NSCLC

Leading the Way in NSCLC Biomarker Testing: An Educational Resource for Advanced Practice Providers (9:35 min)

An educational and interactive summary for advanced practice providers (APP) that offers insight into testing considerations, how to set expectations with patients, and receiving and reviewing test results in NSCLC

Featuring Andrew S. Guinigundo, an APP and Director of Precision Oncology at Cincinnati Cancer Advisors

Exploring Biomarker Testing in NSCLC: Actionable Biomarkers and Current Testing Guidelines (3:16 min)

An educational medical short for healthcare professionals about actionable biomarkers, biomarker testing, and current biomarker testing guidelines in advanced NSCLC

Featuring Dr. Ticiana Leal from the Winship Cancer Institute at Emory University School of Medicine

Examining Biomarker Testing Gaps in NSCLC (3:57 min)

An educational medical short for healthcare professionals about guideline recommendations, the benefits of broad biomarker testing, and current biomarker testing patterns and gaps in advanced NSCLC

Featuring Dr. Ticiana Leal from the Winship Cancer Institute at Emory University School of Medicine

Overcoming Biomarker Testing Barriers in NSCLC (5:04 min)

An educational medical short for healthcare professionals about biomarker testing methods, testing barriers, and considerations to overcome testing barriers in advanced NSCLC

Featuring Dr. Ticiana Leal from the Winship Cancer Institute at Emory University School of Medicine

Key Considerations in Biomarker Testing Journey in NSCLC (10:29 min)

A podcast featuring Dr. Pranil K. Chandra, who discusses the importance of testing, practice considerations for tissue preservation, and scenarios where liquid biopsy may be preferred

Considerations for Biomarker Testing in NSCLC (11:00 min)

A podcast featuring Dr. David R. Braxton, who discusses the importance of biomarker testing in clinical practice, improving turnaround time, and strategies for documentation

Have You Tested Your NSCLC Patients for All Actionable Biomarkers? (00:29 seconds)

A short animated video reminding healthcare professionals to test their eligible NSCLC patients for all actionable biomarkers

Downloadable resources for you and your practice

Download the NSCLC Biomarker Testing Flashcard

A resource that contains an overview of the biomarker testing landscape in NSCLC, including prevalence, guideline recommendations, and considerations for testing

Download the How to Identify Flashcard

A 2-page document that summarizes how to test, record, and report on KRAS G12C as part of a biopsy, as well as a list of reference labs in the United States that test for KRAS G12C

Download the NGS Considerations Flashcard

A resource that outlines the coverage for
next-generation sequence testing for many commercial and Medicare insurance plans. The resource also includes a chart of steps for support coverage and prior authorization information

Download the LUNGevity Discussion Guide*

A resource developed by LUNGevity that can be used when discussing comprehensive biomarker testing with patients, featuring common questions patients may have and how to answer them

Download the LUNGevity Biomarker Factsheet*

A resource developed by LUNGevity about comprehensive biomarker testing for your patients with lung cancer. It also includes helpful tips on when to use biomarker testing and some current barriers that you may face. Please see an additional reference to support the information in this factsheet: Billingy NE, et al. Cancers (Basel). 2021;13:4282.

Download the Faculty Perspectives Comprehensive Biomarker Testing in NSCLC [Guide]

A longer-form guide providing a detailed overview of NSCLC biomarker testing. The overview incorporates data and guideline recommendations. These are enhanced further by perspectives and considerations on testing topics from expert faculty Maria E. Arcila, MD, Mark A. Socinski, MD, and Lauren Welch, MSN, NP-C, AOCNP

Download the PMC Summary: Clinical Process Gaps in Lung Cancer and Personalized Medicine

A single-page resource that lists and explains practice gaps in offering targeted therapy to patients with NSCLC. Please see an additional reference to support the information in this resource: Sadik H, et al. JCO Precision Oncology. 2022;6:e2200246.

Downloadable resources for your patients

Download the Biomarker Wallet Card

A wallet card for patients to complete with their care team to help keep track of their individual biomarker status and facilitate conversations

Download the Patient Brochure

A patient-focused disease state education resource that helps inform patients about biomarker testing, the KRAS G12C mutation, and other helpful guidance about these topics

Download the Importance of KRAS G12C Testing Handout

A brief but detailed overview featuring questions and answers for patients about the purpose of biomarker testing, what testing for KRAS G12C is meant to accomplish, and how to get tested

Download the Patient Biomarker Resource*

A 2-page outline that offers step-by-step guidance for a patient's journey through metastatic NSCLC, including testing, biomarker analysis, and personalized therapy. The second page includes a list of questions for a patient to ask their healthcare providers during each step of the journey. This educational resource was developed in partnership with The Academy of Oncology Nurse and Patient Navigators®

Download the LUNGevity Quick Facts Flashcard* Download Spanish Version

An informative list of frequently asked questions that patients may have about biomarker testing developed by LUNGevity. The flashcard may help provide patients with a clearer understanding of what occurs with biomarker testing and may help better inform their treatment decisions

Download the LUNGevity Important Things to Know Factsheet* Download Spanish Version

LUNGevity has developed a patient-directed overview about biomarker testing, what is involved, and what to expect with the testing process

Download the LUNGevity Biomarker Conversation Starter* Download Spanish Version

A short discussion guide created by LUNGevity to help patients navigate conversations with their healthcare providers. The questions offer a linear path to help patients understand what tests they may need and what the results of those tests mean for them

Download the LUNGevity Patients' Bill of Rights* Download Spanish Version

A LUNGevity-created summary of patients' rights and considerations when undergoing comprehensive biomarker testing. This Bill of Rights helps set expectations for patients who may not be familiar with the process of biomarker testing

Download the Cancer Support Resource: Coping with the Stigma of Lung Cancer*

A resource offering support and guidance around a patient's lung cancer diagnosis. The resource looks at potential obstacles stemming from others' reactions to the news, how to cope with or overcome those obstacles, and other organizations or outlets that offer support for patients

Download the Cancer Support Community Resource: Preparing Patients for Your Doctor's Visit*

A conversation guide for patients to use when talking about their lung cancer diagnosis with their doctor. The guide provides a detailed list of potential care team members and their roles, topics to discuss with members of their care team, helpful questions to ask, and other organizational tools and skills for the patient to help themselves and to help others help them

*These third-party resources are for your information only. Amgen does not endorse and is not responsible for the content included in these resources.

Learn more about testing for KRAS G12C >

KRAS, Kirsten rat sarcoma; NGS, next-generation sequencing; NSCLC, non-small cell lung cancer.

Additional KRAS G12C support and resources for you and your practice

Videos and podcasts

Downloadable resources for you and your practice

Downloadable resources for your patients

Additional KRAS G12C support and
resources for you and your practice